19971-12-1Relevant articles and documents
Facile synthesis of 3-formyl-2,2,5,5-tetramethyl-1-oxypyrroline
Stork, Sebastian W.,Makinen, Marvin W.
, p. 1309 - 1312 (1999)
The spin-label compound 3-formyl-2,2,5,5-tetramethyl-1-oxypyrroline was synthesized from inexpensive starting materials in a sequence of four experimentally undemanding, but high yield achieving transformations. The key step is reduction of an N-methoxy-N-methylcarboxamide to an aldehyde functionality.
Synthesis of Chiral Spin-Labeled Amino Acids
Vuong, Wayne,Mosquera-Guagua, Fabricio,Sanichar, Randy,McDonald, Tyler R.,Ernst, Oliver P.,Wang, Lei,Vederas, John C.
supporting information, p. 10149 - 10153 (2019/12/24)
Spin-labeled amino acids (SLAAs) are often used to determine intermolecular distances and conformations in proteins via double electron-electron resonance. Currently available SLAAs can be difficult to incorporate selectively and have little resemblance to natural side chains in proteins. Enantioselective synthesis of three spin-labeled l-amino acids is described, starting from readily available 2,2,6,6-tetramethyl-4-piperidinone. These SLAAs better replicate canonical residues in proteins and aim for biological incorporation via genetic incorporation or solid-phase peptide synthesis.
LIQUID CRYSTAL COMPOSITION CONTAINING NITROGEN-CONTAINING CYCLIC COMPOUND AND LIQUID CRYSTAL DISPLAY DEVICE
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Paragraph 0159; 0160; 0161, (2016/08/17)
The disclosure shows a liquid crystal composition that contains a compound having an effect of preventing photolysis of the liquid crystal composition and having high solubility in the liquid crystal composition, and that satisfies at least one of characteristics such as high maximum temperature, low minimum temperature, small viscosity, suitable optical anisotropy, large positive or negative dielectric anisotropy, large specific resistance, high stability to ultraviolet light or heat, and a suitable elastic constant, etc. and so on. The disclosure shows a liquid crystal composition that contains a compound having the following azolidine ring (Q-1) or azepane ring (Q-2), a liquid crystal display device and so on.