19992-50-8 Usage
General Description
ML329 is a small molecule chemical compound that has been identified as a potent and selective inhibitor of the enzyme phosphodiesterase 10A (PDE10A). This enzyme is involved in the regulation of intracellular levels of the signaling molecule cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). ML329 has shown promising potential in the treatment of various neurological and psychiatric disorders, including schizophrenia, bipolar disorder, and Huntington's disease. Its ability to modulate the levels of cAMP and cGMP in the brain makes it a valuable tool for studying the role of these signaling molecules in health and disease. Overall, ML329 represents a novel and valuable tool for the study and potential treatment of various neurological and psychiatric conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 19992-50-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,9,9 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 19992-50:
(7*1)+(6*9)+(5*9)+(4*9)+(3*2)+(2*5)+(1*0)=158
158 % 10 = 8
So 19992-50-8 is a valid CAS Registry Number.
19992-50-8Relevant articles and documents
BIOMARKERS PREDICTIVE OF CANCER CELL RESPONSE TO ML329 OR A DERIVATIVE THEREOF
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Page/Page column 96, (2020/06/19)
The present invention is based in part on the identification of biomarkers, including NQOl, NRF2 and KEAP1, predictive of cancer cell responsiveness to treatment with ML 329 or a derivative thereof.
Synthesis of substituted benzoquinones and naphthoquinones with potential antituberculous activity
Roushdi,Mikhail,Chaaban
, p. 269 - 270 (2007/10/07)
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