199934-16-2 Usage
Uses
UCL 1684 is a highly potent and selective, nonpeptidic blocker of the Apamin-sensitive Ca2+-activated K+ channel of which inhibition potentially terminates and protects against atrial fibrillation.
Biological Activity
Highly potent, non-peptidic blocker of the apamin-sensitive Ca 2+ -activated K + channel (SK Ca ) (IC 50 = 3 nM in rat sympathetic neurons). Blocks hSK1 and rSK2 channels expressed in HEK 293 cells with IC 50 values of 762 and 364 pM respectively.
Check Digit Verification of cas no
The CAS Registry Mumber 199934-16-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,9,3 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 199934-16:
(8*1)+(7*9)+(6*9)+(5*9)+(4*3)+(3*4)+(2*1)+(1*6)=202
202 % 10 = 2
So 199934-16-2 is a valid CAS Registry Number.
InChI:InChI=1/C34H28N4.2C2HF3O2/c1-3-10-33-29(8-1)31-16-18-37(33)23-27-6-5-7-28(20-27)24-38-19-17-32(30-9-2-4-11-34(30)38)36-22-26-14-12-25(13-15-26)21-35-31;2*3-2(4,5)1(6)7/h1-20H,21-24H2;2*(H,6,7)/b35-31+,36-32+;;