29886-64-4 Usage
Description
4-(3-THIENYL)BENZOIC ACID, with the chemical formula C13H10O2, is a benzoic acid derivative featuring a thienyl group at the 4-position. 4-(3-THIENYL)BENZOIC ACID is recognized for its potential as a building block in the synthesis of bioactive molecules and has garnered interest in pharmaceutical research due to its possible medicinal properties, such as anti-inflammatory and anti-cancer effects. Moreover, it has been explored for its utility as a fluorescent probe for detecting RNA secondary structures, highlighting its unique structure and promising biological activities for further research and development in chemistry and medicine.
Uses
Used in Pharmaceutical Research:
4-(3-THIENYL)BENZOIC ACID is used as a building block for the synthesis of various bioactive molecules, contributing to the development of new pharmaceutical agents.
Used in Organic Synthesis:
4-(3-THIENYL)BENZOIC ACID is utilized as a key intermediate in the creation of complex organic compounds, facilitating advancements in chemical synthesis techniques.
Used in Medicinal Applications:
4-(3-THIENYL)BENZOIC ACID is used as a potential therapeutic agent for its anti-inflammatory and anti-cancer properties, offering new avenues for the treatment of various diseases.
Used in Biomedical Research:
4-(3-THIENYL)BENZOIC ACID is employed as a fluorescent probe for detecting RNA secondary structures, aiding in the study of RNA biology and its implications in disease mechanisms.
Used in Chemical Research and Development:
4-(3-THIENYL)BENZOIC ACID is used as a subject of study for its unique structure and potential biological activities, driving innovation in the fields of chemistry and medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 29886-64-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,8,8 and 6 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 29886-64:
(7*2)+(6*9)+(5*8)+(4*8)+(3*6)+(2*6)+(1*4)=174
174 % 10 = 4
So 29886-64-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H8O2S/c12-11(13)9-3-1-8(2-4-9)10-5-6-14-7-10/h1-7H,(H,12,13)
29886-64-4Relevant articles and documents
CoIII-Catalyzed Isonitrile Insertion/Acyl Group Migration Between C?H and N?H bonds of Arylamides
Kalsi, Deepti,Barsu, Nagaraju,Sundararaju, Basker
supporting information, p. 2360 - 2364 (2018/02/22)
A general efficient and site-selective cobalt-catalyzed insertion of isonitrile into C?H and N?H bonds of arylamides through C?H bond activation and alcohol assisted intramolecular trans-amidation is demonstrated. This straightforward approach overcomes the limitation by the presence of strongly chelating groups. Isolation of CoIII-isonitrile complex B has been achieved for the first time to understand the reaction mechanism.
Structural modifications of salicylates: Inhibitors of human CD81-receptor HCV-E2 interaction
Holzer, Marcel,Ziegler, Sigrid,Neugebauer, Alexander,Kronenberger, Bernd,Klein, Christian D.,Hartmann, Rolf W.
experimental part, p. 478 - 484 (2009/04/04)
Starting point of the present paper was the result of a virtual screening using the open conformation of the large extracellular loop (LEL) of the CD81-receptor (crystal structure: PDB-ID: 1G8Q). After benzyl salicylate had been experimentally validated to be a moderate inhibitor of the CD81-LEL-HCV-E2 interaction, further optimization was performed and heterocyclic-substituted benzyl salicylate derivatives were synthesized. The compounds were tested for their ability to inhibit the interaction of a fluorescence-labeled antibody to CD81-LEL using HUH7.5 cells. No compound showed an increase concerning the inhibition of the protein-protein interaction compared to benzyl salicylate.
A novel anthracenyl tagged protecting group for "phase-switching" applications in parallel synthesis
Li, Xin,Abell, Chris,Ladlow, Mark
, p. 4189 - 4194 (2007/10/03)
A new "phase-switching" protecting group 1 that facilitates the parallel synthesis of carboxylic acids, esters, and carboxamides is described. Its use permits chemistries to be performed in solution, which may be conveniently monitored with conventional a
