30162-02-8 Usage
General Description
Thiazolo[4,5-d]pyrimidine-2,7-diamine, also known as TPD, is a chemical compound with a unique molecular structure. It is a heterocyclic compound that contains both sulfur and nitrogen atoms in its ring. TPD has been widely studied for its potential pharmaceutical applications, particularly in the development of new drugs for various medical conditions. It has shown promising biological activities, including anti-cancer, anti-inflammatory, and antimicrobial properties. Additionally, TPD has been investigated for its potential use in organic light-emitting diodes (OLEDs) and organic semiconductor materials, due to its unique electronic and photophysical properties. Overall, TPD is a versatile chemical compound with a range of potential applications in various fields, making it a subject of ongoing research and interest in the scientific community.
Check Digit Verification of cas no
The CAS Registry Mumber 30162-02-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,1,6 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 30162-02:
(7*3)+(6*0)+(5*1)+(4*6)+(3*2)+(2*0)+(1*2)=58
58 % 10 = 8
So 30162-02-8 is a valid CAS Registry Number.
30162-02-8Relevant articles and documents
A convenient synthesis of thiazolopyrimidines, thiazolodipyrimidines and heterocyclothiazolopyrimidines
Sherif,Youssef,Mobarak,Abdel-Fattah
, p. 9561 - 9572 (2007/10/02)
Ethyl 4-aryl-6-substituted-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxyla tes 1 reacted with bromomalononitrile (2) to give ethyl 3-amino-5-aryl-2-cyano-7-substituted-5H-thiazolo[3,2-a]pyrimidine-6-ca rboxylates 3. The latter compounds reacted with formic acid, hydroxylamine hydrochloride and with formamide to give 9H-3,4-dihydrothiazolo[3,2-a:4,5-b]dipyrimidine-8-carboxylates 5, 1H,8H-pyrazolo[3,4-d]thiazolo[3,2-a]pyrimidine-7-carboxylates 8 and 2,7-diaminothiazolo[4,5-d]pyrimidine (7), respectively. Compounds 1b,e reacted with chloroacetyl chloride to yield ethyl 5-aryl-3-oxo-7-substituted-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6- carboxylates 9a,b which coupled with arenediazonium chlorides to give the corresponding 2-arylhydrazone derivatives 10a,b. Compound 9a adds α-cyanocinnamonitriles 12a-c to yield ethyl 2-amino-4-aryl-3-cyano-9-(4-methoxyphenyl)-7-methyl-4H,9H-pyrano[2,3-d ]thiazolo[3,2-a]pyrimidine-8-carboxylates 13a-c. Refluxing 1b-d with phenacyl bromide produced ethyl 5-aryl-7-methyl-3-phenyl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylates 14a-c.
