799279-93-9Relevant articles and documents
A-366833: A novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane α4β2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models
Ji, Jianguo,Bunnelle, William H.,Anderson, David J.,Faltynek, Connie,Dyhring, Tino,Ahring, Philip K.,Rueter, Lynne E.,Curzon, Peter,Buckley, Michael J.,Marsh, Kennan C.,Kempf-Grote, Anita,Meyer, Michael D.
, p. 1253 - 1262 (2008/02/09)
5-[(1R,5S)-3,6-Diazabicyclo[3.2.0]heptan-6-yl]nicotinonitrile (A-366833) is a novel nicotinic acetylcholine receptor (nAChR) ligand that binds to the agonist-binding site ([3H]-cytisine) with Ki value of 3.1 nM and exhibits agonist s
Diazabicyclic central nervous system active agents
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, (2008/06/13)
Compounds of formula I pharmaceutical compositions of these compounds, and use of said compositions to control synaptic transmission in mammals.