799773-53-8Relevant articles and documents
The synthesis of potential Neramexane metabolites: Cis- and trans-3-amino-1,3,5,5-tetramethylcyclohexanecarboxylic acids
Trifanova, Dina,Trifonova, Marija,Jirgensons, Aigars,Kauss, Valerjans,Pugovich, Osvalds,Kalvinsh, Ivars,Quack, Guenter
, p. 8145 - 8147 (2007/10/03)
A seven step synthetic route toward potential Neramexane metabolites cis- and trans-3-amino-1,3,5,5-tetramethylcyclohexanecarboxylic acids, cis-1 and trans-1, has been developed from isophorone. The synthetic procedure represents a useful method for the preparation of γ-amino acids with both amino and carboxyl groups situated at tertiary carbon atoms.