79979-69-4Relevant articles and documents
Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties
Kawai, Megumi,BaMaung, Nwe Y.,Fidanze, Steve D.,Erickson, Scott A.,Tedrow, Jason S.,Sanders, William J.,Vasudevan, Anil,Park, Chang,Hutchins, Charles,Comess, Kenneth M.,Kalvin, Douglas,Wang, Jieyi,Zhang, Qian,Lou, Pingping,Tucker-Garcia, Lora,Bouska, Jennifer,Bell, Randy L.,Lesniewski, Richard,Henkin, Jack,Sheppard, George S.
, p. 3574 - 3577 (2007/10/03)
We have screened molecules for inhibition of MetAP2 as a novel approach toward antiangiogenesis and anticancer therapy using affinity selection/mass spectrometry (ASMS) employing MetAP2 loaded with Mn2+ as the active site metal. After a series
Degradation of Reed's Base and Combes' Base
Singh, Prem Narayan,Sinha, Girish Kumar,Singh, Nityanand
, p. 874 - 876 (2007/10/02)
Synthesis of 1,2,3,4-tetrahydro derivatives of Reed's base and its complete degradation to 2-amino-1-naphthoic acid are described.Similarly synthesis of 1,2,3,4-tetrahydro-2,4-dimethyl-6,7-benzoquinoline (Combes' base) and its complete degradation to 2-amino-3-naphthoic acid is also described.This constitutes an evidence that Reed's base is angular while Combes' base is linear.