99863-12-4Relevant articles and documents
Asymmetric synthesis of α-alkylated aldehydes using terminal epoxide-derived chiral enamines
Hodgson, David M.,Kaka, Naeem S.
supporting information; experimental part, p. 9958 - 9960 (2009/06/30)
(Chemical Equation Presented) Effective discrimination: Efficient lithium amide-induced terminal epoxide-enamine transformation provides the first enamines capable of generating α-alkylated aldehydes with high asymmetric induction by intermolecular nucleophilic substitution (see scheme).