1000002-07-2Relevant academic research and scientific papers
Aerobic synthesis of N-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts
Cazin, Catherine S. J.,Lazreg, Fa?ma,Slawin, Alexandra M. Z.,Vasseur, Marie
, p. 482 - 491 (2020)
A new catalytic strategy for the one-pot synthesis of N-sulfonylamidines is described. The cationic copper(I) complexes were found to be highly active and efficient under mild conditions in air and in the absence of solvent. A copper acetylide is proposed as key intermediate in this transformation.
Phosphoryl azides as versatile new reaction partners in the Cu-catalyzed three-component couplings
Seok, Hwan Kim,Doo, Young Jung,Chang, Sukbok
, p. 9769 - 9771 (2007)
(Chemical Equation Presented) Phosphoryl azide was successfully employed as an efficient reacting partner in the Cu-catalyzed three-component reaction with 1-alkynes and amines to produce the corresponding phosphoryl amidines in high yields. A range of fr
Synthesis and SAR of sulfonyl- and phosphoryl amidine compounds as anti-resorptive agents
Lee, Myung Yun,Kim, Myung Hee,Kim, Jinho,Kim, Seok Hwan,Kim, Bum Tae,Jeong, In Howa,Chang, Sukbok,Kim, Seong Hwan,Chang, Sung-Youn
experimental part, p. 541 - 545 (2010/04/05)
Sulfonyl amidines (1) and phosphoryl amidines (2), which were efficiently synthesized via a Cu-catalyzed one pot reaction, showed potent anti-bone resorptive activity in vitro. Structure activity relationship studies led to the identification of numerous
