1000024-91-8

Basic information

• Product Name: [(3-Hydroxy-5-(4-methylphenyl)-pyridine-2-carbonyl)-amino]-acetic acid methyl ester
• Synonyms: [(3-Hydroxy-5-(4-methylphenyl)-pyridine-2-carbonyl)-amino]-acetic acid methyl ester
• CAS NO: 1000024-91-8
• Molecular Weight: 300.314
• Mol File: 1000024-91-8.mol

Chemical Properties

• CAS DataBase Reference: [(3-Hydroxy-5-(4-methylphenyl)-pyridine-2-carbonyl)-amino]-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(3-Hydroxy-5-(4-methylphenyl)-pyridine-2-carbonyl)-amino]-acetic acid methyl ester(1000024-91-8)
• EPA Substance Registry System: [(3-Hydroxy-5-(4-methylphenyl)-pyridine-2-carbonyl)-amino]-acetic acid methyl ester(1000024-91-8)

Safety Data

• Hazardous Substances Data: 1000024-91-8(Hazardous Substances Data)

Upstream product

• 1393534-89-8 3-(benzyloxy)-5-bromopicolinic acid 
• 1393534-88-7 3-(benzyloxy)-5-bromopicolinonitrile 
• 573675-25-9 5-bromo-3-nitropyridine-2-carbonitrile 

Downstream Products

• 1000025-10-4 [(3-Hydroxy-5-(4-methylphenyl)pyridine-2-carbonyl)amino]-acetic acid 

Relevant articles and documents

An improved and scalable synthesis of N-(5-(4-cyanophenyl)-3-hydroxypicolinoyl)glycine, a promising PHD2 inhibitor for the treatment of anemia

Abstract An improved and scalable synthetic method of N-(5-(4-cyanophenyl)-3-hydroxypicolinoyl)glycine, a promising inhibitor of PHD2, is described. The optimized route staring from commercially available 5-bromo-3-nitropicolinonitrile takes only five chemical steps and has a dramatically increased total yield of 37.6% without chromatographic purifications.