1000197-91-0

Upstream product

• 97145-88-5 3-chloro-N-methylpropan-1-amine hydrochloride 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 1000197-92-1 phenylmethyl N-[3-[4-[3-chloro-1,6-dihydro-1-[(2S)-2-methylbutyl]-6-oxo-5-(1H-pyrazol-1-yl)-2-pyrazinyl]-3,5-difluorophenoxy]propyl]-N-methylcarbamate 
• 1193511-87-3 phenylmethyl N-[3-[4-[4-chloro-2-methyl-1-(4-methylphenyl)-1H-imidazol-5-yl]-3,5-difluorophenoxy]propyl]-N-methylcarbamate 

Relevant academic research and scientific papers

PYRAZINONES AS CELLULAR PROLIFERATION INHIBITORS

This invention pertains to a method of inhibiting undesired animal cellular proliferation said method comprising contacting an animal cell with a compound of Formula 1 and all pharmaceutically acceptable, salts, N-oxides, hydrates, solvates, or geometric and stereoisomers thereof: Formula (I) wherein R1 is NR4 R5, N=CR19 R21 OR6, G1 or G2; or C1-C8 alkyl, C2-C8 alkenyl, each optionally substituted; A is O, S or NR7; R2 is cyano, NR8-N=CR9 R10 or NC(=O)R30; or a 5- or 6-membered heteroaromatic ring, each ring or ring system optionally substituted; R3 is H, halogen, cyano, C1-C6 alkyl; J is C1- C8 alkyl or phenyl, optionally substituted; and R4, R5, R6, R7, R8, R9, R10, R19, R21, R30, G1 and G2 are defined in the disclosure.