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3-[4-(Trifluoromethyl)phenyl]prop-2-yn-1-ol, also known as 3-[4-(Trifluoromethyl)phenylethynyl]phenol, is a phenol ether compound that is a fluorinated derivative of 3-phenylprop-2-yn-1-ol. It features a trifluoromethyl group attached to a phenyl ring, giving it unique structural and property characteristics. This organic compound holds potential for various applications, particularly in the pharmaceutical industry, where it can be utilized in the development of novel drug compounds. Its distinctive features make it a subject of interest for research and exploration in medicinal chemistry.

1000198-76-4

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1000198-76-4 Usage

Uses

Used in Pharmaceutical Industry:
3-[4-(Trifluoromethyl)phe...] is used as a chemical intermediate for the synthesis of new drug compounds due to its unique structure and properties. Its trifluoromethyl group and phenyl ring provide opportunities for the development of pharmaceuticals with specific therapeutic targets and improved pharmacokinetic profiles.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 3-[4-(Trifluoromethyl)phe...] is used as a starting material for the design and synthesis of new chemical entities. Its structural features allow for the exploration of various chemical modifications, potentially leading to the discovery of innovative therapeutic agents with enhanced efficacy and selectivity.
Used in Drug Development:
3-[4-(Trifluoromethyl)phe...] is utilized in drug development processes to create novel pharmaceuticals with potential applications in treating various diseases and conditions. Its unique properties may contribute to the development of drugs with improved pharmacological profiles, including better absorption, distribution, metabolism, and excretion characteristics.

Check Digit Verification of cas no

The CAS Registry Mumber 1000198-76-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,1,9 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1000198-76:
(9*1)+(8*0)+(7*0)+(6*0)+(5*1)+(4*9)+(3*8)+(2*7)+(1*6)=94
94 % 10 = 4
So 1000198-76-4 is a valid CAS Registry Number.

1000198-76-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[4-(Trifluoromethyl)phenyl]pyrrolidine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1000198-76-4 SDS

1000198-76-4Downstream Products

1000198-76-4Relevant academic research and scientific papers

RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE

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, (2020/02/06)

Provided herein are compounds as RORγ antagonist having Formula (I). The compounds or pharmaceutical composition thereof can be used for regulating Retinoid-related orphan receptor gamma t (RORγt). Also provided herein are methods of preparation of the compounds and composition thereof, and uses thereof in treating or preventing RORγt mediated inflammation or autoimmune diseases in mammals, particularly humans.

Substituted phenyl methanone derivatives

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Page/Page column 8, (2008/06/13)

The present invention relates to compounds of formula I wherein R1, R2, R3, X, n, and m are as defined herein and to pharmaceutically acceptable acid addition salts thereof, to pharmaceutical compositions containing them,

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