1000271-96-4Relevant academic research and scientific papers
Design, synthesis and in vitro evaluation of mono (2, 2, 2-trifluoroethyl) esters, mono l-amino acid ester prodrugs of acyclic nucleoside phosphonates as anti-HBV agents
Fu, Xiao Zhong,Ou, Yu,Xin, Jan,Yang, Yu She
, p. 1387 - 1390 (2011)
A series of novel mono (2, 2, 2-trifluoroethyl) esters, mono l-amino acid ester prodrugs of acyclic nucleoside phosphonates was synthesized and their in vitro anti-HBVactivity was evaluated in HepG 2 2.2.15 cells. Compound 1d exhibited more potent anti-HB
