1000341-73-0 Usage
Uses
Used in Organic Synthesis:
6-BROMO-3-IODO-5-AZAINDOLE is used as a key intermediate in organic synthesis for the preparation of various biologically active molecules. Its unique structure and functional groups make it a versatile building block for the development of new compounds with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 6-BROMO-3-IODO-5-AZAINDOLE is utilized as a starting material for the synthesis of drug candidates. Its presence in the molecular structure can impart specific pharmacological properties, such as improved binding affinity, selectivity, and bioavailability, which are crucial for the development of effective therapeutic agents.
Used in Medicinal Chemistry:
6-BROMO-3-IODO-5-AZAINDOLE is employed as a research tool in medicinal chemistry to explore its reactivity and interaction with biological systems. Understanding its properties can aid in the design of novel compounds with enhanced therapeutic potential and selectivity for specific targets.
Used in Drug Discovery:
In the field of drug discovery, 6-BROMO-3-IODO-5-AZAINDOLE serves as a valuable compound for high-throughput screening and structure-activity relationship (SAR) studies. Its unique structural features can be exploited to identify new lead compounds and optimize their pharmacological properties for the treatment of various diseases.
Used in Chemical Biology:
6-BROMO-3-IODO-5-AZAINDOLE is also used in chemical biology to study the interactions between small molecules and biological targets, such as proteins, enzymes, and receptors. This knowledge can provide insights into the molecular mechanisms of diseases and facilitate the development of targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 1000341-73-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,3,4 and 1 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1000341-73:
(9*1)+(8*0)+(7*0)+(6*0)+(5*3)+(4*4)+(3*1)+(2*7)+(1*3)=60
60 % 10 = 0
So 1000341-73-0 is a valid CAS Registry Number.
1000341-73-0Relevant academic research and scientific papers
NEW THIENOPYRIMIDINE DERIVATIVES AS NIK INHIBITORS
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Page/Page column 52, (2016/06/06)
The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF-κB-inducing kinase (NIK - also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.
NEW 1-(4-PYRIMIDINYL)-1H-PYRROLO[3,2-c]PYRIDINE DERIVATIVES AS NIK INHIBITORS
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Page/Page column 98, (2015/04/15)
The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF-κB-inducing kinase (NIK -also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.
