1000357-39-0Relevant articles and documents
Potent achiral agonists of the ghrelin (growth hormone secretagogue) receptor. Part I: Lead identification
Heightman, Tom D.,Scott, Jackie S.,Longley, Mark,Bordas, Vincent,Dean, David K.,Elliott, Richard,Hutley, Gail,Witherington, Jason,Abberley, Lee,Passingham, Barry,Berlanga, Manuela,de los Frailes, Maite,Wise, Alan,Powney, Ben,Muir, Alison,McKay, Fiona,Butler, Sharon,Winborn, Kim,Gardner, Christopher,Darton, Jill,Campbell, Colin,Sanger, Gareth
, p. 6584 - 6587 (2007)
High throughput screening combined with efficient datamining and parallel synthesis led to the discovery of a novel series of indolines showing potent in vitro ghrelin receptor agonist activity and acceleration of gastric emptying in rats.
