1000374-22-0

Basic information

• Product Name: 2-amino-8-(4-fluorobenzylidene)-4-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
• Synonyms: 2-amino-8-(4-fluorobenzylidene)-4-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
• CAS NO: 1000374-22-0
• Molecular Formula: C23H19F2N3O
• Molecular Weight: 391.4132664
• Mol File: 1000374-22-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-8-(4-fluorobenzylidene)-4-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-8-(4-fluorobenzylidene)-4-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile(1000374-22-0)
• EPA Substance Registry System: 2-amino-8-(4-fluorobenzylidene)-4-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile(1000374-22-0)

Safety Data

• Hazardous Substances Data: 1000374-22-0(Hazardous Substances Data)

Upstream product

• 4369-13-5 3,5-bis-(4-fluoro-benzylidene)-1-methyl-piperidin-4-one 
• 109-77-3 malononitrile 
• 920030-35-9 (3E,5E)-1-methyl-3,5-bis(4-fluorobenzylidene)piperidin-4-one 
• 1445-73-4 1-Methyl-4-piperidone 
• 459-57-4 4-fluorobenzaldehyde 

Relevant articles and documents

An atom efficient, solvent-free, green synthesis and antimycobacterial evaluation of 2-amino-6-methyl-4-aryl-8-[(E)-arylmethylidene]-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitriles

An atom efficient, green protocol for the synthesis of fifteen 2-amino-6-methyl-4-aryl-8-[(E)-arylmethylidene]-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitriles in quantitative yields from the reaction of 1-methyl-3,5-bis[(E)-arylmethylidene]-te

Application of MCM-41-SO3H as an advanced nanocatalyst for the solvent free synthesis of pyrano[3,2-c]pyridine derivatives

MCM-41-SO3H, an ordered mesoporous silica material in which MCM-41 with covalently anchored sulfonic acid groups was used as an acidic catalyst for the rapid and 'green' synthesis of pyrano[3,2-c]pyridine derivatives under solvent-free conditions. Reusability of the catalyst, high yields, short reaction times, simplicity and easy workup are advantages of this novel synthetic procedure compared to the conventional methods reported in the literature.