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1000376-75-9

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1000376-75-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1000376-75-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,3,7 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1000376-75:
(9*1)+(8*0)+(7*0)+(6*0)+(5*3)+(4*7)+(3*6)+(2*7)+(1*5)=89
89 % 10 = 9
So 1000376-75-9 is a valid CAS Registry Number.

1000376-75-9Relevant academic research and scientific papers

New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists

Manera, Clementina,Cascio, Maria Grazia,Benetti, Veronica,Allara, Marco,Tuccinardi, Tiziano,Martinelli, Adriano,Saccomanni, Giuseppe,Vivoli, Elisa,Ghelardini, Carla,Di Marzo, Vincenzo,Ferrarini, Pier Luigi

, p. 6505 - 6510 (2008/09/20)

A series of new 1,8-naphthyridine and quinoline derivatives were synthesized and evaluated for their cannabinoid receptor affinity. In particular, compounds 2, 5, 11, and 13 showed a high CB2 affinity and CB2 versus CB1 selectivity, in agreement with molecular modeling studies. Furthermore, compound 2 also exhibited in vivo antinociceptive effects.

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