1000387-95-0

Basic information

• Product Name: C₁₄H₁₄N₂O
• Synonyms: C₁₄H₁₄N₂O
• CAS NO: 1000387-95-0
• Molecular Weight: 226.278
• Mol File: 1000387-95-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₄N₂O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₄N₂O(1000387-95-0)
• EPA Substance Registry System: C₁₄H₁₄N₂O(1000387-95-0)

Safety Data

• Hazardous Substances Data: 1000387-95-0(Hazardous Substances Data)

Upstream product

• 872-85-5 pyridine-4-carbaldehyde 
• 2393-23-9 4-methoxy-benzylamine 

Downstream Products

• 1000388-05-5 1-(4-methoxybenzyl)-3,3-difluoro-4-(pyridin-4-yl)azetidin-2-one 

Relevant articles and documents

Chemoselective and stereoselective synthesis of gem-difluoro-β-aminoesters or gem-difluoro-β-lactams from ethylbromodifluoroacetate and imines during Reformatsky reaction

The chemoselective and stereoselective synthesis of gem-difluoro-β-aminoesters or gem-difluoro-β-lactams was investigated from ethylbromodifluoroacetate and imines during Reformatsky reaction. Influence of various reaction parameters, such as nature of the amine part, nature of the chiral auxiliary, was evaluated. High levels of stereoselectivity (up to 98%) were obtained for gem-difluoro-β-aminoesters and gem-difluoro-β-lactams using either (R)-phenylglycinol or (R)-methoxyphenylglycinol.