100041-05-2

Basic information

• Product Name: flazin
• Synonyms: flazin;1-[5-(Hydroxymethyl)furan-2-yl]-9H-pyrido[3,4-b]indole-3-carboxylic acid;Flazine
• CAS NO: 100041-05-2
• Molecular Formula: C17H12N2O4
• Molecular Weight: 308.28818
• Mol File: 100041-05-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 657.1°Cat760mmHg
• Flash Point: 351.2°C
• Appearance: /
• Density: 1.513g/cm³
• Vapor Pressure: 3.69E-18mmHg at 25°C
• Refractive Index: 1.771
• CAS DataBase Reference: flazin(CAS DataBase Reference)
• NIST Chemistry Reference: flazin(100041-05-2)
• EPA Substance Registry System: flazin(100041-05-2)

Safety Data

• Hazardous Substances Data: 100041-05-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H12N2O4/c20-8-9-5-6-14(23-9)16-15-11(7-13(19-16)17(21)22)10-3-1-2-4-12(10)18-15/h1-7,18,20H,8H2,(H,21,22)

Upstream product

• 50-00-0 formaldehyd 
• 1108154-96-6 methyl 1-(furan-2-yl)-9H-pyrido[3,4-b]indole-3-carboxylate 
• 98-01-1 furfural 
• 7303-49-3 DL-tryptophan methyl ester 
• 104537-95-3 1-(5-Acetoxymethyl-furan-2-yl)-9H-β-carboline-3-carboxylic acid methyl ester 
• 104537-94-2 1-(5-Hydroxymethyl-2-furyl)-3-carbomethoxy-9H-pyrido<3,4-b>indole 
• 1242336-87-3 methyl 1-(furan-2-yl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylate 

Downstream Products

• 104537-94-2 1-(5-Hydroxymethyl-2-furyl)-3-carbomethoxy-9H-pyrido<3,4-b>indole 

Relevant articles and documents

β-Carbolines from Japanese sake and soy sauce: Synthesis and biological activity of flazin and yellow substance YS (perlolyrine)

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Cu-catalyzed mild and efficient oxidation of THβCs using air: Application in practical total syntheses of perlolyrine and flazin

A mild, efficient and environmentally benign method for synthesis of aromatic β-carbolines via Cu(ii)-catalyzed oxidation of 1,2,3,4-tetrahydro-β-carbolines (THβCs) was developed, in which air (O2) was used as the clean oxidant. This method has advantages such as environmentally friendliness, mildness, very good tolerance of functional groups, high yielding and easy experiment operation. In addition, this new methodology was successfully applied in the efficient and practical total syntheses of β-carboline alkaloids perlolyrine and flazin.