1000573-99-8Relevant academic research and scientific papers
BENZOTHIOPHENE, THIENOPYRIDINE AND THIENOPYRIMIDINE DERIVATIVES FOR THE MODULATION OF STING
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Page/Page column 94, (2021/02/12)
A compound of formula (I); wherein: W is O or NH; A1 1 is CRAA or N; A22 is CRBB or N; A3A3 is CRCC or N; A44 is CRDD or N; where no more than two of A11, A
PYRAZOLO[3,4-B]PYRAZINE SHP2 PHOSPHATASE INHIBITORS
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Page/Page column 118, (2021/02/26)
The invention provides new pyrazine derivatives of formula (I): or a tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined herein. The invention also provides pharmaceutical compositions comprising sa
HETEROBICYCLIC COMPOUNDS FOR INHIBITING THE ACTIVITY OF SHP2
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Paragraph 0897-0899, (2020/02/16)
A compound of formula (I):wherein Ring A, Q, R1,R2, R3, R4, R5, R6, R7, R8, R9, R10, R11,X, a,b, c and d are as defined in the specification.
PHARMACEUTICAL COMPOUNDS
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Page/Page column 244, (2019/09/18)
The invention provides new pyrazine derivatives of formula (I), or a tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined herein. The invention also provides pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS
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Paragraph 0628, (2017/03/14)
Compounds, methods of use, and processes for making inhibitors of complement Factor D are provided comprising Formula I, I" and I'" or a pharmaceutically acceptable salt or composition thereof. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade. The inhibitors of Factor D described herein reduces the excessive activation of complement.
COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS
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Paragraph 0658, (2017/03/14)
Compounds, methods of use, and processes for making inhibitors of complement Factor D comprising Formula (I), or a pharmaceutically acceptable salt or composition thereof The inhibitors described herein target Factor D and inhibit or regulate the complement cascade. The inhibitors of Factor D described herein reduce the excessive activation of complement.
NRF2 REGULATORS
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, (2015/07/07)
The present invention relates to bis aryl analogs, pharmaceutical compositions containing them and their use as Nrf2 regulators.
ANTI-VIRAL COMPOUNDS
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Page/Page column 155, (2012/06/30)
Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF
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Page/Page column 84, (2010/04/03)
The present application relates to novel substituted 5-aminopyrazoles, methods of production thereof, use thereof alone or in combinations for the treatment and/or prophylaxis of diseases and use thereof for the production of medicinal products for the treatment and/or prophylaxis of diseases.
