1000576-83-9

Basic information

• Product Name: N-Boc-3-dimethylaminopiperidine
• Synonyms: N-Boc-3-dimethylaminopiperidine;eridine
• CAS NO: 1000576-83-9
• Molecular Formula: C₁₂H₂₄N₂O₂
• Molecular Weight: 228.33116
• Mol File: 1000576-83-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 295.4 °C at 760 mmHg
• Flash Point: 132.5 °C
• Appearance: /
• Density: 1.01 g/cm³
• CAS DataBase Reference: N-Boc-3-dimethylaminopiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-3-dimethylaminopiperidine(1000576-83-9)
• EPA Substance Registry System: N-Boc-3-dimethylaminopiperidine(1000576-83-9)

Safety Data

• Hazardous Substances Data: 1000576-83-9(Hazardous Substances Data)

Usage

General Description

N-Boc-3-dimethylaminopiperidine is a chemical compound with the molecular formula C13H24N2O2. It is a tertiary amine derivative of piperidine that contains a tert-butyloxycarbonyl (Boc) protecting group. N-Boc-3-dimethylaminopiperidine is commonly used as a reagent in organic synthesis, particularly in the pharmaceutical industry for the preparation of various drugs and pharmaceutical intermediates. It is also utilized as a building block in the synthesis of a variety of bioactive compounds and in materials science for the functionalization of surfaces. N-Boc-3-dimethylaminopiperidine is a versatile compound with a range of applications in chemical research and production.

InChI:InChI=1/C12H24N2O2/c1-12(2,3)16-11(15)14-8-6-7-10(9-14)13(4)5/h10H,6-9H2,1-5H3/t10-/m1/s1

Upstream product

• 98977-36-7 3-oxo-piperidine-1-carboxylic acid tert-butyl ester 
• 124-40-3 dimethyl amine 

Downstream Products

• 50534-49-1 3-(dimethylamino)piperidine 

Relevant articles and documents

SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1

The invention is directed to substituted pyridine derivatives. Specifically, the invention is directed to compounds according to Formula (Iar): (Iar) wherein Yar, X1ar, X2ar, R1ar, R2ar, R3ar, R4ar and R5ar are as defined herein; or a pharmaceutically acceptable salt or prodrug thereof. The compounds of the invention are selective inhibitors of DNMT1 and can be useful in the treatment of cancer, pre-cancerous syndromes, beta hemoglobinopathy disorders, sickle cell disease, sickle cell anemia, and beta thalassemia, and diseases associated with DNMT1 inhibition. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting DNMT1 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

BIS-PYRIDYLPYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS

The invention provides novel bis-pyridylpyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy and for the treatment of obesity and/or diabetes.