1000577-94-5

Usage

Uses

Used in Organic Synthesis:
3-Bromo-4-iodobenzonitrile is used as a building block in the synthesis of various biologically active compounds due to its unique structure and the presence of bromine and iodine atoms, which can be strategically utilized in chemical reactions.
Used in Pharmaceutical Research:
In pharmaceutical research, 3-Bromo-4-iodobenzonitrile is used as a precursor for the development of new drugs, leveraging its distinct chemical properties to create novel therapeutic agents.
Used in Catalyst Development:
3-Bromo-4-iodobenzonitrile is used as a potential catalyst in certain chemical reactions, taking advantage of its reactive bromine and iodine atoms to facilitate specific transformations.
Used in Material Science:
In the field of material science, 3-Bromo-4-iodobenzonitrile is used in the development of new materials and fine chemicals, capitalizing on its distinct chemical properties to create innovative products with specialized applications.
Used in Laboratory Research:
3-Bromo-4-iodobenzonitrile is used in laboratory research settings for the exploration of its chemical properties and potential applications, with trained professionals conducting experiments in controlled environments to ensure safety and effectiveness.

Upstream product

• 50397-74-5 2-bromo-4-cyanoaniline 
• 873-74-5 4-Aminobenzonitrile 

Downstream Products

• 1616624-62-4 (E)-[2-(2-bromo-4-cyanophenyl)-1,2-diphenylvinyl]trimethylstannane 
• 1616624-67-9 (E)-1,2-bis(2-bromo-4-cyanophenyl)-1,2-diphenylethene 
• 1374636-57-3 3-bromo-4-(((trimethylsilyl)ethynyl)thio)benzonitrile 
• 1374636-51-7 S-(2-bromo-4-cyanophenyl)benzenesulfonothioate 
• 1374636-46-0 C₁₄H₆Br₂N₂S₂ 

Relevant academic research and scientific papers

Gold(I)-Catalyzed Cascade Cyclization Reactions of Allenynes for the Synthesis of Fused Cyclopropanes and Acenaphthenes

A gold-catalyzed reaction of phenylene-tethered allenynes with benzofurans gave 1-(naphth-1-yl)cyclopropa[b]benzofuran derivatives, whereas the reaction of 1-allenyl-2-ethynyl-3-methylbenzene derivatives in the absence of benzofurans gave acenaphthenes in good yields. These results can be rationalized by nucleophilic attack of the alkyne moiety on an activated allene to form a vinyl cation intermediate.

Synthesis of functionalized benzo[b]thiophenes by the intramolecular copper-catalyzed carbomagnesiation of alkynyl(aryl)thioethers

Highly functional: A copper(I)-catalyzed intramolecular carbomagnesiation under mild conditions transforms readily available alkynyl(aryl)thioethers into magnesiated benzothiophenes. Subsequent reaction with various electrophiles (acid chlorides, allyl bromides, aryl halides) provides polyfunctional benzo[b]thiophenes (see scheme). Further modification of the cyclization products affords highly diversified benzothiophene derivatives and new heterocyclic scaffolds.

Palladium-catalyzed aryl amination-heck cyclization cascade: A one-flask approach to 3-substituted indoles

(Chemical Equation Presented) Two for the price of one: A Pd/dppf-based catalyst provides access to the title compounds from 1,2-dihalogenated aromatic compounds and allylic amines in a single reaction flask. The initial aryl amination step occurs with excellent selectivity for the aryl iodide to ensure the formation of a single indole regioisomer, which can be functionalized in situ by N-arylation (see scheme). dba = dibenzylideneacetone, dppf = 1,1′-bis(diphenylphospanyl)ferrocene.