1000588-73-7

Basic information

• Product Name: tert-butyl [(6R)-6-(4-cyanophenyl)-5-isobutyryl-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-3,6-dihydropyrimidin-1(2H)-yl]acetate
• Synonyms: tert-butyl [(6R)-6-(4-cyanophenyl)-5-isobutyryl-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-3,6-dihydropyrimidin-1(2H)-yl]acetate
• CAS NO: 1000588-73-7
• Molecular Weight: 541.57
• Mol File: 1000588-73-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl [(6R)-6-(4-cyanophenyl)-5-isobutyryl-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-3,6-dihydropyrimidin-1(2H)-yl]acetate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl [(6R)-6-(4-cyanophenyl)-5-isobutyryl-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-3,6-dihydropyrimidin-1(2H)-yl]acetate(1000588-73-7)
• EPA Substance Registry System: tert-butyl [(6R)-6-(4-cyanophenyl)-5-isobutyryl-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-3,6-dihydropyrimidin-1(2H)-yl]acetate(1000588-73-7)

Safety Data

• Hazardous Substances Data: 1000588-73-7(Hazardous Substances Data)

Upstream product

• 5292-43-3 bromoacetic acid tert-butyl ester 
• 1000588-65-7 4-{(4R)-5-Isobutyryl-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidin-4-yl}benzonitrile 

Downstream Products

• 1000588-74-8 [(6R)-6-(4-Cyanophenyl)-5-isobutyryl-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-3,6-dihydropyrimidin-1(2H)-yl]acetic acid 

Relevant articles and documents

USE OF1,4-DIARYL-DIHYDROPYRIMIDINE-2-ON DERIVATIVES FOR TREATING PULMONARY ARTERIAL HYPERTENSION

The present application relates to the use of 1,4-diaryldihydropyrimidin-2-one derivatives of the formula (I) for the treatment and/or prophylaxis of pulmonary arterial hypertension and other types of pulmonary hypertension, and to the use thereof for the manufacture of medicaments for the treatment and/or prophylaxis of pulmonary arterial hypertension and other types of pulmonary hypertension.