1000606-07-4

Basic information

• Product Name: N-[1-(3-isopropyl-4-triisopropylsilanyloxybenzyl)-7-methyl-1H-indol-4-yl]-2-(1H-tetrazol-5-yl)acetamide
• Synonyms: N-[1-(3-isopropyl-4-triisopropylsilanyloxybenzyl)-7-methyl-1H-indol-4-yl]-2-(1H-tetrazol-5-yl)acetamide
• CAS NO: 1000606-07-4
• Molecular Weight: 560.815
• Mol File: 1000606-07-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[1-(3-isopropyl-4-triisopropylsilanyloxybenzyl)-7-methyl-1H-indol-4-yl]-2-(1H-tetrazol-5-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[1-(3-isopropyl-4-triisopropylsilanyloxybenzyl)-7-methyl-1H-indol-4-yl]-2-(1H-tetrazol-5-yl)acetamide(1000606-07-4)
• EPA Substance Registry System: N-[1-(3-isopropyl-4-triisopropylsilanyloxybenzyl)-7-methyl-1H-indol-4-yl]-2-(1H-tetrazol-5-yl)acetamide(1000606-07-4)

Safety Data

• Hazardous Substances Data: 1000606-07-4(Hazardous Substances Data)

Upstream product

• 21743-75-9 (1H-tetrazol-5-yl)-acetic acid 
• 1000605-27-5 1-(3-isopropyl-4-triisopropylsilanyloxybenzyl)-7-methyl-1H-indol-4-ylamine 

Relevant articles and documents

NOVEL 6-5 BICYCIC HETEROCYCLIC DERIVATIVE AND MEDICAL USE THEREOF

An object of the present invention is to provide a medicament as a thyroid hormone receptor ligand which is sufficient in drug efficacy and safety, and has the excellent action as a drug. The present invention provides a compound represented by the following general formula (I) or a pharmaceutically acceptable salt thereof: [wherein [Chemical Formula 2] is a single bond or a double bond; A is -CH2- or -CO-; X, Y, and Z are each independently a nitrogen atom or a carbon atom; R1 is a hydrogen atom or an aralkyl group; R2 is an alkyl group or an aralkyl group, etc.; R3 is a hydrogen atom or an alkyl group, etc.; R4 is a hydrogen atom or an alkyl group; R5 is a hydrogen atom, an alkyl group or a halo lower alkyl group, etc.; R6 is a hydrogen atom or an alkyl group; R7 is a hydrogen atom, etc.; R8 is a hydrogen atom, or an alkyl group, etc.; and E is -NHCO-G-COR12, etc. (wherein G is a single bond or an alkylene group, and R12 is a hydroxy group or an alkoxy group)].