1000606-86-9Relevant academic research and scientific papers
A Robust and Broadly Applicable Cobalt-Catalyzed Cross-Coupling of Functionalized Bench-Stable Organozinc Pivalates with Unsaturated Halides
Hammann, Jeffrey M.,Lutter, Ferdinand H.,Haas, Diana,Knochel, Paul
, p. 1082 - 1086 (2017)
We report a robust and broadly applicable CoCl2-catalyzed cross-coupling between functionalized aryl and heteroaryl zinc pivalates and various electron-poor aryl and heteroaryl halides (X=Cl, Br, I). Couplings with (E)- or (Z)-bromo- or iodo-alkenes proceed with retention of configuration. Also, alkynyl bromides react with arylzinc pivalates providing arylated alkynes.
Nickel-catalyzed carboannulation reaction of o-bromobenzyl zinc bromide with unsaturated compounds
Deng, Ruixue,Sun, Liangdong,Li, Zhi
, p. 5207 - 5210 (2008/09/17)
(Chemical Equation Presented) A number of indenes have been prepared in good yields by treating o-bromobenzyl zinc bromide 1 with various terminal and internal alkynes in the presence of a nickel catalyst. The nickel-catalyzed carboannulation reaction was successfully extended to the synthesis of indane derivatives by reaction of 1 with acrylates and styrene.
