1000680-23-8Relevant articles and documents
Cyclic allyl carbamates in stereoselective syn SE′ processes: Synthetic approach to sarcodictyins and eleutherobin
Dhulut, Sylvie,Bourin, Arnaud,Lannou, Marie-Isabelle,Fleury, Etienne,Lensen, Nathalie,Chelain, Evelyne,Pancrazi, Ange,Ardisson, Janick,Fahy, Jacques
, p. 5235 - 5243 (2007)
Our synthetic approach of marine diterpenoids sarcodictyins A and B and eleutherobin relies on the one-step attachment of a C5-C9 side chain at the C10 position. The C1, C10 cis-disubstituted cyclohexene derivative is obtained in 86 % yield with total stereoselectivity. The reaction is based on a syn S E′ process involving a cyclic (Z)-allyl diisopropylcarbamate. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.