1000682-39-2Relevant academic research and scientific papers
Phenyl α-bromovinyl sulfone in cycloadditions with azomethine ylides: An unexpected facile aromatization of the cycloadducts into pyrroles
Kudryavtsev, Konstantin V.,Ivantcova, Polina M.,Churakov, Andrei V.,Vasin, Victor A.
experimental part, p. 4300 - 4303 (2012/09/22)
Phenyl α-bromovinyl sulfone reacts with glycine ester Schiff bases regioselectively in the presence of catalytic amounts of AgOAc and DBU yielding polysubstituted pyrrolidine cycloadducts. Utilization of excess DBU induces subsequent facile aromatization of the cycloadducts and affords 5-arylpyrrole-2-carboxylic acid esters in 39-85% yields in a single step.
Transition metal-catalyzed synthesis of pyrroles from dienyl azides
Dong, Huijun,Shen, Meihua,Redford, Joanne E.,Stokes, Benjamin J.,Pumphrey, Ashley L.,Driver, Tom G.
, p. 5191 - 5194 (2008/09/17)
(Chemical Equation Presented) A range of 2,5-disubstituted and 2,4,5-trisubstituted pyrroles can be synthesized from dienyl azides at room temperature using catalytic amounts of Znl2 or Rh2(O 2CC3F7)4.
