1000683-03-3Relevant academic research and scientific papers
A highly efficient route to C-3 alkyl-substituted indoles via a metal-free transfer hydrogenation
Chen, Cai,Feng, Huan-Xi,Li, Zhi-Long,Cai, Pin-Wen,Liu, Yan-Kai,Shan, Lian-Hai,Zhou, Xian-Li
, p. 3774 - 3776 (2014/07/07)
A highly efficient route to C-3 alkyl-substituted indoles via completely metal-free catalytic transfer hydrogenation of 3-indolemethanols was developed. This process proceeds via vinylogous iminium intermediates formed in situ in the presence of Br?nsted
Novel Bronsted acid catalyzed three-component alkylations of indoles with N-phenylselenophthalimide and styrenes
Zhao, Xiaodan,Yu, Zhengkun,Xu, Tongyu,Wu, Ping,Yu, Haifeng
, p. 5263 - 5266 (2008/09/17)
(Chemical Equation Presented) Novel and efficient Bronsted acid (p-TsOH) catalyzed inter- and intramolecular Friedel-Crafts alkylations have been developed to synthesize selenated three-component coupling and selenation-cyclization indole derivatives. Chemical removal of the phenylseleno moiety was investigated, and the reaction mechanisms were discussed.
