1000690-91-4 Usage
Uses
De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride, is an impurity of Cetirizine (C281100, 2HCl); a nonsedating type histamine H1-receptor antagonist and a major metabolite of Hydroxyzine (H996500). Pharmacological activity of Cetirizine resides primarily in the (R)-isomer. Also antihystaminic.
Check Digit Verification of cas no
The CAS Registry Mumber 1000690-91-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,6,9 and 0 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1000690-91:
(9*1)+(8*0)+(7*0)+(6*0)+(5*6)+(4*9)+(3*0)+(2*9)+(1*1)=94
94 % 10 = 4
So 1000690-91-4 is a valid CAS Registry Number.
1000690-91-4Relevant articles and documents
Glycine transporter-1 inhibitors
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Page/Page column 31, (2008/06/13)
The present invention provides compounds that are glycine transporter 1 (hereinafter referred to as GlyT-1) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of GlyT1 such as cognitive disorders associated with Schizophrenia, ADHD (attention deficit hyperactivity disorder), MCI (mild cognitive impairment), and the like. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
