100072-53-5Relevant academic research and scientific papers
REACTIONS EN MILIEU HETEROGENE SOLIDE-LIQUIDE FAIBLEMENT HYDRATE : LA REACTION DE WITTIG DANS LE SYSTEME HYDROXIDES ALCALINS/SOLVANT ORGANIQUE APROTIQUE
Le Bigot, Yves,Delmas, Michel,Gaset, Antoine
, p. 1057 - 1072 (2007/10/02)
The Wittig reaction carried out in a slightly hydrated solid-liquid media constituted by a solid alkaline hydroxide and an organic phase which includes the phosphonium salt and the aldehyde leads easily to the corresponding alkene with very good yields specially with furanic aldehydes.The ylide formation at the interface appears as the most important step of this condensation.
REACTIONS EN MILIEU HETEROGENE SOLIDE-LIQUIDE FAIBLEMENT HYDRATE: II - LA REACTION DE WITTIG DANS LES SYSTEMES CARBONATES ALCALINS/SOLVANT ORGANIQUE APROTIQUE
Bigot, Yves Le,Delmas, Michel,Gaset, Antoine
, p. 339 - 350 (2007/10/02)
The use of alkaline carbonates in a slighty hydrated solid-liquid aprotic organic media allowed the synthesis of alkenes from polyfunctionnal aldehydes or activated ketones with high yield in a Z preferential stereochemistry.The reaction mechanism proposed takes in account the specific use of water on the solvation of cationic species at the solid-liquid interface to explain the Z.E alkene ratio.
