1000801-76-2

Basic information

• Product Name: 1-(3-Methoxypropyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
• Synonyms: 1-(3-Methoxypropyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1H-Pyrazole, 1-(3-Methoxypropyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;(1-(3-METHOXYPROPYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER
• CAS NO: 1000801-76-2
• Molecular Formula: C₁₃H₂₃BN₂O₃
• Molecular Weight: 266.14432
• Mol File: 1000801-76-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 375.243 °C at 760 mmHg
• Flash Point: 180.74 °C
• Appearance: /
• Density: 1.059 g/cm3
• Vapor Pressure: 0 mmHg at 25°C
• Refractive Index: 1.497
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.00±0.10(Predicted)
• CAS DataBase Reference: 1-(3-Methoxypropyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-Methoxypropyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole(1000801-76-2)
• EPA Substance Registry System: 1-(3-Methoxypropyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole(1000801-76-2)

Safety Data

• Hazardous Substances Data: 1000801-76-2(Hazardous Substances Data)

Usage

General Description

1-(3-Methoxypropyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole is a chemical compound with the molecular formula C13H22BNO2. It is a pyrazole derivative that contains a 1,3,2-dioxaborolane moiety and a 3-methoxypropyl group. 1-(3-Methoxypropyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole has potential applications in organic synthesis, medicinal chemistry, and material science. It can be used as a building block in the preparation of pharmaceuticals, agrochemicals, and functional materials. Furthermore, it may also exhibit interesting biological activities that make it a valuable target for further research and development. Additionally, the boron-containing group in this compound can impart unique reactivity and selectivity in certain chemical reactions, making it a useful tool for synthetic chemists.

InChI:InChI=1S/C13H23BN2O3/c1-12(2)13(3,4)19-14(18-12)11-9-15-16(10-11)7-6-8-17-5/h9-10H,6-8H2,1-5H3

Upstream product

• 1183903-41-4 4-bromo-1-(3-methoxypropyl)-1H-pyrazole 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1254837-91-6 N-(4-(1-(3-methoxypropyl)-1H-pyrazol-4-yl)-2-(trifluoromethoxy)benzyl)-2,6-dioxo-1-(pyridin-2-ylmethyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide 

Relevant articles and documents

MAP4K4 INHIBITORS

This invention relates to compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these compounds, for example in a method of treatmentof cardiac conditions.In particular, the present invention relates to compounds of formula (I):

HETEROARYL COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF

The present invention provides herein is a heteroaryl compound or a stereoisomer, a geometric isomer, a tautomer, a racemate, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, as well as a pharmaceutical composition containing the compound disclosed herein. The present invention also provides herein is use of the compound or the pharmaceutical composition thereof disclosed herein in the manufacture of a medicine for treating autoimmune diseases or proliferative diseases.

2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXAMIDES

Disclosed are sEH inhibitors of formula (I), wherein the variables are as defined herein, as well as pharmaceutical compositions, kits, and articles of manufacture that contain such compounds. Also disclosed are methods and intermediates for making the compounds and the use of such compounds to treat various disorders, diseases, and conditions associated with sEH.