1000890-38-9

Basic information

• Product Name: methyl (thiophenyl 5-N-butanoyl-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosyl)onate
• Synonyms: methyl (thiophenyl 5-N-butanoyl-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosyl)onate
• CAS NO: 1000890-38-9
• Molecular Weight: 611.667
• Mol File: 1000890-38-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl (thiophenyl 5-N-butanoyl-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosyl)onate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (thiophenyl 5-N-butanoyl-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosyl)onate(1000890-38-9)
• EPA Substance Registry System: methyl (thiophenyl 5-N-butanoyl-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosyl)onate(1000890-38-9)

Safety Data

• Hazardous Substances Data: 1000890-38-9(Hazardous Substances Data)

Upstream product

• 106-31-0 butanoic acid anhydride 
• 118977-25-6 methyl (phenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-galacto-2-nonulopyranoside)onate 
• 67670-69-3 N-acetyl-4,7,8,9-tetra-O-acetyl-2-chloro-2-deoxyneuraminic acid methyl ester 
• 19342-33-7 N-acetyl neuraminic acid 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Chemical Synthesis and Enzymatic Testing of CMP-Sialic Acid Derivatives

The cycloSal approach has been used in the past for the synthesis of a range of phosphorylated bioconjugates. In those reports, cycloSal nucleotides were allowed to react with different phosphate nucleophiles. With glycopyranosyl phosphates as nucleophile

Transsialidase from Trypanosoma cruzi for regio- and stereoselective synthesis of N-acyl-modified sialylated oligosaccharides and measurement of transfer rates

Recombinant transsialidase from Trypanosoma cruzi (TcTS) was used for the sialylation with natural and non-natural derivatives of neuraminic acid. Neu5Ac-α(2→3)-Gal-β(1→6)-Glc-αOMe was prepared in 80% yield. Correspondingly, the modified trisaccharide derivatives Neu5Prop-α(2 →3)-Gal-β(1 →6)-GlcαOMe (32%) and Neu5Gc-α(2→3)-Gal-β(1→6)-Glc-αOMe (Prop = propanoyl, Gc = glycolyl) were obtained in 60 % yield, respectively.