Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1000896-45-6

Post Buying Request

1000896-45-6 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1000896-45-6 Usage

Description

5-(2-Methoxy-1-Methylethoxy)-1H-Pyrazol-3-aMine, also known as TAK-242, is a chemical compound with potential anti-inflammatory and anti-septic properties. It is a small molecule inhibitor of Toll-like receptor 4 (TLR4) signaling, which is essential in the body's immune response. TAK-242 effectively blocks TLR4-mediated activation of nuclear factor kappa B (NF-κB) and production of pro-inflammatory cytokines, making it a promising candidate for treating various inflammatory conditions and sepsis.

Uses

Used in Pharmaceutical Industry:
5-(2-Methoxy-1-Methylethoxy)-1H-Pyrazol-3-aMine is used as an anti-inflammatory agent for its ability to block TLR4-mediated activation of NF-κB and production of pro-inflammatory cytokines, offering potential therapeutic benefits in controlling inflammation and preventing septic shock.
Used in Sepsis Treatment:
In the medical field, 5-(2-Methoxy-1-Methylethoxy)-1H-Pyrazol-3-aMine is used as a potential treatment for sepsis, leveraging its capacity to inhibit TLR4 signaling and reduce the severity of septic shock.
Used in Research Applications:
5-(2-Methoxy-1-Methylethoxy)-1H-Pyrazol-3-aMine is utilized as a research tool to study the role of TLR4 in immune responses and inflammation, aiding in the development of new therapeutic strategies for inflammatory conditions.
Used in Drug Development:
As a small molecule inhibitor of TLR4, 5-(2-Methoxy-1-Methylethoxy)-1H-Pyrazol-3-aMine is employed in the development of new drugs targeting inflammatory pathways, with the aim of discovering more effective treatments for a range of diseases characterized by excessive inflammation.

Check Digit Verification of cas no

The CAS Registry Mumber 1000896-45-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,8,9 and 6 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1000896-45:
(9*1)+(8*0)+(7*0)+(6*0)+(5*8)+(4*9)+(3*6)+(2*4)+(1*5)=116
116 % 10 = 6
So 1000896-45-6 is a valid CAS Registry Number.

1000896-45-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(1-methoxypropan-2-yloxy)-1H-pyrazol-5-amine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1000896-45-6 SDS

1000896-45-6Upstream product

1000896-45-6Downstream Products

1000896-45-6Relevant articles and documents

Novel Compounds

-

Page/Page column 97-98, (2008/06/13)

There is provided a compound of formula (I): processes for the manufacture thereof, pharmaceutical compositions thereof and uses in therapy.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1000896-45-6