1000896-45-6 Usage
Description
5-(2-Methoxy-1-Methylethoxy)-1H-Pyrazol-3-aMine, also known as TAK-242, is a chemical compound with potential anti-inflammatory and anti-septic properties. It is a small molecule inhibitor of Toll-like receptor 4 (TLR4) signaling, which is essential in the body's immune response. TAK-242 effectively blocks TLR4-mediated activation of nuclear factor kappa B (NF-κB) and production of pro-inflammatory cytokines, making it a promising candidate for treating various inflammatory conditions and sepsis.
Uses
Used in Pharmaceutical Industry:
5-(2-Methoxy-1-Methylethoxy)-1H-Pyrazol-3-aMine is used as an anti-inflammatory agent for its ability to block TLR4-mediated activation of NF-κB and production of pro-inflammatory cytokines, offering potential therapeutic benefits in controlling inflammation and preventing septic shock.
Used in Sepsis Treatment:
In the medical field, 5-(2-Methoxy-1-Methylethoxy)-1H-Pyrazol-3-aMine is used as a potential treatment for sepsis, leveraging its capacity to inhibit TLR4 signaling and reduce the severity of septic shock.
Used in Research Applications:
5-(2-Methoxy-1-Methylethoxy)-1H-Pyrazol-3-aMine is utilized as a research tool to study the role of TLR4 in immune responses and inflammation, aiding in the development of new therapeutic strategies for inflammatory conditions.
Used in Drug Development:
As a small molecule inhibitor of TLR4, 5-(2-Methoxy-1-Methylethoxy)-1H-Pyrazol-3-aMine is employed in the development of new drugs targeting inflammatory pathways, with the aim of discovering more effective treatments for a range of diseases characterized by excessive inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 1000896-45-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,8,9 and 6 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1000896-45:
(9*1)+(8*0)+(7*0)+(6*0)+(5*8)+(4*9)+(3*6)+(2*4)+(1*5)=116
116 % 10 = 6
So 1000896-45-6 is a valid CAS Registry Number.
1000896-45-6Relevant articles and documents
Novel Compounds
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Page/Page column 97-98, (2008/06/13)
There is provided a compound of formula (I): processes for the manufacture thereof, pharmaceutical compositions thereof and uses in therapy.