1000931-04-3

Basic information

• Product Name: TERT-BUTYL 3-HYDROXY-4-PHENYLPIPERIDINE-1-CARBOXYLATE
• Synonyms: TERT-BUTYL 3-HYDROXY-4-PHENYLPIPERIDINE-1-CARBOXYLATE;1-Boc-3-Hydroxy-4-phenylpiperidine;3-Hydroxy-4-phenyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
• CAS NO: 1000931-04-3
• Molecular Formula: C₁₆H₂₃NO₃
• Molecular Weight: 277.35872
• Mol File: 1000931-04-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: TERT-BUTYL 3-HYDROXY-4-PHENYLPIPERIDINE-1-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 3-HYDROXY-4-PHENYLPIPERIDINE-1-CARBOXYLATE(1000931-04-3)
• EPA Substance Registry System: TERT-BUTYL 3-HYDROXY-4-PHENYLPIPERIDINE-1-CARBOXYLATE(1000931-04-3)

Safety Data

• Hazardous Substances Data: 1000931-04-3(Hazardous Substances Data)

Usage

General Description

TERT-BUTYL 3-HYDROXY-4-PHENYLPIPERIDINE-1-CARBOXYLATE is a chemical compound with the molecular formula C19H27NO3. It is a piperidine derivative with a tert-butyl group and a phenyl group attached to the piperidine ring. TERT-BUTYL 3-HYDROXY-4-PHENYLPIPERIDINE-1-CARBOXYLATE is commonly used in pharmaceutical research and drug development as a building block for the synthesis of various bioactive molecules. It exhibits potential pharmacological activities and may have applications in the treatment of various medical conditions. Additionally, it is important to handle and use this chemical with care, following strict safety protocols to avoid any potential hazards.

Upstream product

• 100-59-4 phenylmagnesium chloride 
• 161157-50-2 tert-butyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate 
• 40807-61-2 4-hydroxy-4-phenylpiperidin 
• 85838-94-4 N-Boc-1,2,3,6-tetrahydropyridine 

Relevant articles and documents

Iron-Catalyzed Tunable and Site-Selective Olefin Transposition

The catalytic isomerization of C-C double bonds is an indispensable chemical transformation used to deliver higher-value analogues and has important utility in the chemical industry. Notwithstanding the advances reported in this field, there is compelling demand for a general catalytic solution that enables precise control of the C═C bond migration position, in both cyclic and acyclic systems, to furnish disubstituted and trisubstituted alkenes. Here, we show that catalytic amounts of an appropriate earth-abundant iron-based complex, a base and a boryl compound, promote efficient and controllable alkene transposition. Mechanistic investigations reveal that these processes likely involve in situ formation of an iron-hydride species which promotes olefin isomerization through sequential olefin insertion/β-hydride elimination. Through this strategy, regiodivergent access to different products from one substrate can be facilitated, isomeric olefin mixtures commonly found in petroleum-derived feedstock can be transformed to a single alkene product, and unsaturated moieties embedded within linear and heterocyclic biologically active entities can be obtained.

Piperidine derivatives having renin inhibiting activity

Novel piperidine derivatives, their manufacture and use as medicaments, are disclosed. The invention is concerned with the novel piperidine derivatives of general formula I wherein R1, R2, R3, R4, Q, X, Z, m and n are as described herein.