1000979-81-6

Basic information

• Product Name: 4-methyl-N-(3-oxo-1-phenyl-propyl)-benzenesulfonamide
• Synonyms: 4-methyl-N-(3-oxo-1-phenyl-propyl)-benzenesulfonamide
• CAS NO: 1000979-81-6
• Molecular Weight: 303.382
• Mol File: 1000979-81-6.mol

Chemical Properties

• CAS DataBase Reference: 4-methyl-N-(3-oxo-1-phenyl-propyl)-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-(3-oxo-1-phenyl-propyl)-benzenesulfonamide(1000979-81-6)
• EPA Substance Registry System: 4-methyl-N-(3-oxo-1-phenyl-propyl)-benzenesulfonamide(1000979-81-6)

Safety Data

• Hazardous Substances Data: 1000979-81-6(Hazardous Substances Data)

Upstream product

• 1001060-81-6 (3S)-(4-toluenesulfonyl)amino-3-phenylpropionitrile 
• 39551-05-8 4-methyl-N-(1-phenylbut-3-enyl)benzenesulfonamide 
• 118917-59-2 (R)-N-(2-hydroxy-1-phenylethyl)-4-methyl-S-methylenebenzenesulfinamide 
• 56613-80-0 D-2-phenylglycinol 
• 875-74-1 (R)-phenylglycine 

Downstream Products

• 1018786-83-8 C₂₂H₂₉NO₅S 
• 936012-01-0 (2S,4S)-2-phenyl-4-propyl-N-tosylazetidine 
• 936012-00-9 (2S,4R)-2-phenyl-4-propyl-N-tosylazetidine 
• 936011-99-3 (2S,4S)-2-ethyl-4-phenyl-1-tosylazetidine 
• 936011-98-2 (2R,4S)-2-benzyl-4-ethyl-1-tosylazetidine 
• 936011-91-5 (S)-2-phenyl-1-tosylazetidine 
• 936012-16-7 N-(3-cyano-3-hydroxy-1-phenyl-propyl)-4-methyl-benzenesulfonamide 
• 936012-14-5 N-(3-hydroxy-1-phenyl-hexyl)-4-methyl-benzenesulfonamide 
• 936011-96-0 N-(3-hydroxy-1-phenyl-hexyl)-4-methyl-benzenesulfonamide 
• 936012-13-4 N-(3-hydroxy-1-phenyl-pentyl)-4-methyl-benzenesulfonamide 
• 936011-95-9 N-(3-hydroxy-1-phenyl-pentyl)-4-methyl-benzenesulfonamide 
• 143371-09-9 (S)-N-(3-hydroxy-1-phenylpropyl)-4-methylbenzenesulfonamide 

Relevant articles and documents

Asymmetric allylation of sulfonyl imines catalyzed by in situ generated Cu(II) complexes of chiral amino alcohol based Schiff bases

A catalytic route for enantioselective synthesis of homoallyl amines through Cu(II)-Schiff base catalyzed reaction of allyltin with aryl, alkenyl-substituted N-sulfonylimines is described. The allylation reaction is promoted by a simple in situ generated Cu(II )-amino alcohol based Schiff base complex. The addition of allyltin to aldimines delivers the desired products up to 90% yield and 98% enantiomeric excess (ee). Based on experimental observations a probable mechanism was proposed for this reaction. The current methodology was extended to the synthesis of b-phenylalanine in good yield and very good enantioselectivity.

A convenient synthetic route to enantiopure N-tosylazetidines from α-amino acids

A general and convenient synthetic route to various chiral 2-substituted- and 2,4-disubstituted-N-tosylazetidines (ee >99%) is described in good overall yields starting from chiral α-amino acids using very simple chemistry.

Lewis acid-mediated unprecedented ring-opening rearrangement of 2-Aryl-N-tosylazetidines to enantiopure (E)-allylamines

A highly efficient strategy for Cu(OTf)2-mediated ring-opening of 2-aryl-N-Mosylazetidines in polar and coordinating solvents followed by an unprecedented rearrangement to substituted achiral and chiral (E)-allylamines (ee >99%) is reported. Th