1000980-60-8

Basic information

• Product Name: CEFTAZIDIME IMPURITY A
• Synonyms: CEFTAZIDIME IMPURITY A;1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-en-3-yl]methyl]pyridinium inner salt;Ceftazidime EP Impurity A;a2-Ceftazidime (>80%)
• CAS NO: 1000980-60-8
• Molecular Formula: C22H22N6O7S2
• Molecular Weight: 546.57608
• Product Categories: Chiral Reagents, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 1000980-60-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Amber Vial, Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
• Stability: Hygroscopic, Light Sensitive
• CAS DataBase Reference: CEFTAZIDIME IMPURITY A(CAS DataBase Reference)
• NIST Chemistry Reference: CEFTAZIDIME IMPURITY A(1000980-60-8)
• EPA Substance Registry System: CEFTAZIDIME IMPURITY A(1000980-60-8)

Safety Data

• Hazardous Substances Data: 1000980-60-8(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 1000980-60-8 differently. You can refer to the following data:
1. A Ceftazidime isomer, an impurity of Ceftazidime (C244100).
2. 2-Ceftazidime, 90% (Ceftazidime EP Impurity A) is a Ceftazidime isomer, an impurity of Ceftazidime (C244100).

Upstream product

• 72558-82-8 ceftazidime 

Relevant articles and documents

Novel approach for the conversion of natural Δ3 cephalosporin derivatives into corresponding Δ2 cephalosporin derivatives

(Chemical Equation Presented) A simple one pot synthetic method for the isomerization of cephem double bond from the natural 3-position to 2-cephem positions is affected by silylation. Thus cephalosporin acids are treated with N-trimethylsilylacetamide (MSA) or N,O-bis(trimethylsilyl)acetamide (BSA) and the resulting silyl esters are treated with triethylamine at ambient temperature in the same pot to afford Δ2-cephalosporins, which are potentially related compounds in cephalosporin antibacterial compounds.