1000981-83-8Relevant academic research and scientific papers
Divergent synthesis of arylated pyridin-2(1H)-one derivatives via metal-catalysed cross-coupling processes
Siddle, Jamie S.,Batsanov, Andrei S.,Caldwell, Stuart T.,Cooke, Graeme,Bryce, Martin R.
experimental part, p. 6138 - 6149 (2010/09/15)
1,5-Di(hetero)arylated-pyridin-2(1H)-one derivatives have been readily obtained in good yields starting from 2-fluoro-5-pyridylboronic acid. The sequence comprises three steps: (i) palladium-catalysed Suzuki-Miyaura reaction; (ii) base-catalysed hydrolysi
Synthetic entries to substituted bicyclic pyridones
Cheng, Dachen,Croft, Laura,Abdi, Muna,Lightfoot, Andrew,Gallagher, Timothy
, p. 5175 - 5178 (2008/09/17)
(Chemical Equation Presented) The synthesis of 6,6- and 5,6-bicyclic pyridone scaffolds has been completed using (i) an intramolecular Mitsunobu reaction and/or (ii) hydrolysis of a bicyclic pyridinium salt intermediate. Regioselective functionalization o
