1000997-01-2Relevant academic research and scientific papers
Synthesis of 5-hydroxy-2-(naphth-2-yl)chromone derivatives
Patoilo, Diana T.,Silva, Artur M. S.,Pinto, Diana C. G. A.,Tome, Augusto C.,Cavaleiro, Jose A. S.
, p. 1345 - 1350 (2008/09/18)
(Chemical Equation Presented) The Diels-Alder reaction of 5-hydroxy-2-styrylchromones with ortho-benzoquinodimethane, generated "in situ" by thermal extrusion of sulfur dioxide from 1,3-dihydrobenzo[c] thiophene 2,2-dioxide, leads to 2-(3-aryl-1,2,3,4-tetrahydronaphth-2-yl)-5- hydroxychromones. These cycloadducts were dehydrogenated with DDQ, using classical thermal reflux conditions and microwave irradiation, affording the corresponding 2-(3-arylnaphth-2-yl)-5-hydroxychromones in high yields (48-96%).
