1001013-59-7

Upstream product

• 271-63-6 7-Azaindole 
• 3058-39-7 4-iodobenzonitrile 

Downstream Products

• 1001013-61-1 methyl 4-(1H-pyrrolo[2,3-b]pyridin-1-yl)benzimidate hydrochloride 
• 1001013-63-3 (E)-N'-(pyrimidin-5-yl)-4-(1H-pyrrolo[2,3-b]pyridin-1-yl)benzamidine 
• 1001013-65-5 (E)-N'-(2-methylpyridin-4-yl)-4-(1H-pyrrolo[2,3-b]pyridin-1-yl)benzamidine 
• 1001014-11-4 C₂₈H₃₁N₅O₂ 
• 1001014-13-6 N'-(6-(trifluoromethyl)pyridin-3-yl)-4-(1H-pyrrolo[2,3-b]pyridin-1-yl)benzamidine 
• 1001014-20-5 tert-butyl 4-(4-(1H-pyrrolo[2,3-b]pyridin-1-yl)benzamido)benzylmethylcarbamate 
• 1001013-60-0 (E)-N'-(4-methoxyphenyl)-4-(1H-pyrrolo[2,3-b]pyridin-1-yl)benzamidine 
• 1001014-69-2 1-(4-(1H-pyrrolo[2,3-b]pyridin-1-yl)phenyl)-2-(pyridin-3-yl)ethanone 
• 1001014-22-7 tert-butyl 4-(2-(4-(1H-pyrrolo[2,3-b]pyridin-1-yl)phenyl)-4-(thiazol-2-yl)-1H-imidazol-1-yl)benzylmethylcarbamate 
• 1001014-77-2 1-(4-(4-(pyridin-3-yl)-1H-pyrazol-3-yl)phenyl)-1H-pyrrolo[2,3-b]pyridine 
• 1001013-62-2 (E)-4-(1H-pyrrolo[2,3-b]pyridin-1-yl)-N'-(thiazol-2-yl)benzamidine 

Relevant academic research and scientific papers

Copper-catalyzedortho-selective direct sulfenylation ofN-aryl-7-azaindoles with disulfides

A copper-catalyzed direct C-H chalcogenation ofN-aryl-azaindoles with disulfides is described. This transformation was performed using Earth abundant Cu(OAc)2as a catalyst, benzoic acid as an additive, air as a terminal oxidant, and readily available diaryl and dialkyldisulfides (or diselenide) as chalcogenation reagents. High functional group tolerance and excellent regioselectivity are demonstrated by the efficient preparation of a wide range ofortho-sulfenylation-7-azaindoles.

SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS

The invention pertains to heteroaromatic compounds of the formula I, as defined herein, that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE10. The invention also relates to pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders.