1001067-54-4Relevant articles and documents
Self-assembly of fluorescent inclusion complexes in competitive media including the interior of living cells
Gassensmith, Jeremiah J.,Arunkumar, Easwaran,Barr, Lorna,Baumes, Jeffrey M.,DiVittorio, Kristy M.,Johnson, James R.,Noll, Bruce C.,Smith, Bradley D.
, p. 15054 - 15059 (2007)
Anthracene-containing tetralactam macrocycles are prepared and found to have an extremely high affinity for squaraine dyes in chloroform (log K a = 5.2). Simply mixing the two components produces highly fluorescent, near-infrared inclusion comp
High-Frequency Mechanostimulation of Cell Adhesion
Kadem, Laith F.,Suana, K. Grace,Holz, Michelle,Wang, Wei,Westerhaus, Hannes,Herges, Rainer,Selhuber-Unkel, Christine
, p. 225 - 229 (2017)
Cell adhesion is regulated by molecularly defined protein interactions and by mechanical forces, which can activate a dynamic restructuring of adhesion sites. Previous attempts to explore the response of cell adhesion to forces have been limited to applying mechanical stimuli that involve the cytoskeleton. In contrast, we here apply a new, oscillatory type of stimulus through push–pull azobenzenes. Push–pull azobenzenes perform a high-frequency, molecular oscillation upon irradiation with visible light that has frequently been applied in polymer surface relief grating. We here use these oscillations to address single adhesion receptors. The effect of molecular oscillatory forces on cell adhesion has been analyzed using single-cell force spectroscopy and gene expression studies. Our experiments demonstrate a reinforcement of cell adhesion as well as upregulated expression levels of adhesion-associated genes as a result of the nanoscale “tickling” of integrins. This novel type of mechanical stimulus provides a previously unprecedented molecular control of cellular mechanosensing.
Red emitting neutral fluorescent glycoconjugates for membrane optical imaging
Redon, Sébastien,Massin, Julien,Pouvreau, Sandrine,De Meulenaere, Evelien,Clays, Koen,Queneau, Yves,Andraud, Chantal,Girard-Egrot, Agnés,Bretonniére, Yann,Chambert, Stéphane
, p. 773 - 787 (2014/05/06)
A family of neutral fluorescent probes was developed, mimicking the overall structure of natural glycolipids in order to optimize their membrane affinity. Nonreducing commercially available di- or trisaccharidic structures were connected to a push-pull ch