1001094-89-8

Basic information

• Product Name: (S)-4-(1-amino-ethyl)-phenol hydrobromid
• Synonyms: (S)-4-(1-amino-ethyl)-phenol hydrobromid
• CAS NO: 1001094-89-8
• Molecular Weight: 218.093
• Mol File: 1001094-89-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (S)-4-(1-amino-ethyl)-phenol hydrobromid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-(1-amino-ethyl)-phenol hydrobromid(1001094-89-8)
• EPA Substance Registry System: (S)-4-(1-amino-ethyl)-phenol hydrobromid(1001094-89-8)

Safety Data

• Hazardous Substances Data: 1001094-89-8(Hazardous Substances Data)

Usage

General Description

(S)-4-(1-amino-ethyl)-phenol hydrobromide is a chemical compound that has potential applications in the pharmaceutical industry. It has a molecular formula of C8H12BrNO and a molecular weight of 214.09 g/mol. The compound is a hydrobromide salt of (S)-4-(1-amino-ethyl)-phenol, which is a chiral phenol derivative. It is a white to off-white crystalline solid that is soluble in water and methanol. (S)-4-(1-amino-ethyl)-phenol hydrobromid may have uses in the development of pharmaceuticals, particularly in the treatment of certain medical conditions due to its potential pharmacological properties. However, further research and studies are needed to fully understand its potential uses and effects.

Upstream product

• 6298-96-0 (S)-1-(4-methoxyphenyl)ethylamine 

Downstream Products

• 645391-89-5 benzyl N-[(1S)-1-(4-hydroxyphenyl)ethyl]carbamate 
• 1620690-56-3 (R)-tert-butyl 3-(4-((S)-1-(benzyloxycarbonylamino)ethyl)phenoxy)pyrrolidine-1-carboxylate 
• 931093-42-4 (S)-tert-butyl 1-(4-hydroxyphenyl)ethylcarbamate 
• 1443670-31-2 (S)-N-(1-(4-hydroxyphenyl)ethyl)cyclopropanecarboxamide 
• 1443670-30-1 (S)-3-(1-(4-hydroxyphenyl)ethyl)-1,1-dimethylurea 
• 1443670-29-8 (S)-N-(1-(4-hydroxyphenyl)ethyl)acetamide 
• 1443670-53-8 (S)-N-(1-(4-(1-(3-hydroxyphenyl)azetidin-3yl-oxy)phenyl)ethyl)acetamide 
• 1443670-47-0 tert-butyl (S)-1-(4-(azetidin-3-yloxy)phenyl)ethylcarbamate 
• 1443669-58-6 (S)-N-(1-(4-(1-(3-(cyclopropylmethoxy)phenyl)azetidin-3-yloxy)phenyl)ethyl)-acetamide 
• 1443669-55-3 C₂₃H₂₃FN₄O₂ 
• 1443669-53-1 (S)-N-(1-(4-(1-(5-cyclopropylpyrimidin-2-yl)azetidin-3-yloxy)phenyl)ethyl)acetamide 
• 1443670-40-3 (S)-N-(1-(4-(azetidin-3-yl-oxy)phenyl)ethyl)acetamide 
• 1443670-39-0 tert-butyl (S)-1-(4-(1-benzhydrylazetidin-3-yl-oxy)phenyl)ethylcarbamate 
• 1443670-38-9 C₂₄H₃₀N₂O₅ 

Relevant articles and documents

COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BROMODOMAIN-CONTAINING PROTEINS

The present invention relates to bifunctional compounds, which find utility as modulators of targeted ubiquitination, especially inhibitors of a variety of polypeptides and other proteins which are degraded and/or otherwise inhibited by bifunctional compounds according to the present invention. In particular, the present invention is directed to compounds, which contain on one end a VHL ligand which binds to the ubiquitin ligase and on the other end a moiety which binds a target protein such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of that protein. The present invention exhibits a broad range of pharmacological activities associated with compounds according to the present invention, consistent with the degradation/inhibition of targeted polypeptides.

PYRIMIDINE-SUBSTITUTED PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

The invention relates to new pyrrolidine derivatives of the formula (I), wherein R1 to R3, Ar, L T and n are as defined in the description and claims, to their use as medicaments, to methods for their therapeutic use and to pharmaceu

AZETIDINE DERIVATIVES

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