1001183-84-1

Basic information

• Product Name: 5-isothiocyanatoquinoline
• Synonyms: 5-isothiocyanatoquinoline
• CAS NO: 1001183-84-1
• Molecular Formula: C₁₀H₆N₂S
• Molecular Weight: 186.23304
• Mol File: 1001183-84-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-isothiocyanatoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-isothiocyanatoquinoline(1001183-84-1)
• EPA Substance Registry System: 5-isothiocyanatoquinoline(1001183-84-1)

Safety Data

• Hazardous Substances Data: 1001183-84-1(Hazardous Substances Data)

Usage

General Description

5-isothiocyanatoquinoline is a chemical compound with the molecular formula C10H6N2S. It is a quinoline derivative with an isothiocyanate functional group attached to the 5-position of the quinoline ring. 5-isothiocyanatoquinoline is a yellowish solid that is sparingly soluble in water but more soluble in organic solvents such as chloroform and acetone. 5-isothiocyanatoquinoline has been studied for its potential applications in organic synthesis and as a building block for the development of pharmaceuticals and agrochemicals. It has also been investigated for its antibacterial and antifungal properties, as well as its potential use in fluorescent sensors and imaging probes.

Upstream product

• 611-34-7 5-Aminoquinoline 
• 463-71-8 thiophosgene 

Downstream Products

• 1001172-70-8 C₂₅H₂₆ClN₇O 

Relevant articles and documents

NOVEL BICYCLIC THIAZOLE COMPOUNDS

The present invention relates to novel bicyclic thiazole compounds that inhibit Traf2- and Nck-interacting kinase (TNIK), and as such are useful as TNIK inhibitors administered to cancer patients, especially to solid cancer patients such as colorectal cancer, pancreatic cancer, non-small cell lung cancer, prostate cancer or breast cancer. The bicyclic thiazole compounds are showed by a next formula (I). (wherein R1, R2, R3 and Q are as defined in the specification), or a pharmaceutically acceptable salt thereof.

2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: Orally bioavailable compounds

Structure-activity relationships and efforts to optimize the pharmacokinetic profile of a class of 2-arylimino-5,6-dihydro-4H-1,3-thiazines as cannabinoid receptor agonists are described. Among the compounds examined, compound 14 showed potent affinity and high selectivity for CB2, and compound 23 showed potent affinities against CB1 and CB2. These compounds displayed oral bioavailability.