100119-63-9

Upstream product

• 40137-29-9 2-methyl-4-chlorobenzaldehyde 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 1221962-39-5 3-(4-chloro-2-methylphenyl)-4-(5-iodo-2-benzimidazolyl)butanoic acid monohydrochloride 
• 104095-31-0 3-(4-chloro-2-methyl-phenyl)-glutaric acid-anhydride 

Relevant academic research and scientific papers

ALLOSTERIC PROTEIN KINASE MODULATORS

The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.

ALLOSTERIC PROTEIN KINASE MODULATORS

The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.