1001203-03-7

Basic information

• Product Name: 3-Ethynyl-4-methyl-benzoic acid
• Synonyms: 3-Ethynyl-4-methyl-benzoic acid
• CAS NO: 1001203-03-7
• Molecular Formula: C₁₀H₈O₂
• Molecular Weight: 160.16932
• EINECS: -0
• Mol File: 1001203-03-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 323.5±35.0 °C(Predicted)
• Appearance: /
• Density: 1.19±0.1 g/cm3(Predicted)
• PKA: 4.16±0.10(Predicted)
• CAS DataBase Reference: 3-Ethynyl-4-methyl-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Ethynyl-4-methyl-benzoic acid(1001203-03-7)
• EPA Substance Registry System: 3-Ethynyl-4-methyl-benzoic acid(1001203-03-7)

Safety Data

• Hazardous Substances Data: 1001203-03-7(Hazardous Substances Data)

Usage

General Description

3-Ethynyl-4-methyl-benzoic acid is a chemical compound with the molecular formula C11H8O2. It is a derivative of benzoic acid and contains a triple bond between the carbon atoms, giving it the ethynyl group in its structure. 3-Ethynyl-4-methyl-benzoic acid is used in organic synthesis and pharmaceutical research as a building block for the production of various drugs and pharmaceuticals. It is also used in the development of materials for electronics and optoelectronics due to its unique chemical structure. Additionally, 3-Ethynyl-4-methyl-benzoic acid may have potential applications in the field of medicinal chemistry and drug development.

Upstream product

• 82998-57-0 3-iodo-4-toluic acid 
• 90347-66-3 methyl 3-iodo-4-methylbenzoate 
• 1255099-13-8 methyl 3-ethynyl-4-methylbenzoate 

Downstream Products

• 1001203-04-8 C₁₅H₁₂N₄O₂ 
• 1098102-70-5 C₂₂H₂₆N₂O₄S 
• 1098102-80-7 C₁₇H₁₁ClF₃NO 
• 957147-18-1 3-ethynyl-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide 
• 943319-70-8 ponatinib 
• 1416241-81-0 3-ethynyl-4-methylbenzoyl chloride 

Relevant articles and documents

Urea-substituted alkynyl pyrimidine or urea-substituted alkynyl pyridine compound as well as composition and application thereof

The invention relates to urea-substituted alkynyl pyrimidine or urea-substituted alkynyl pyridine compounds with a formula (I) or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, pharmaceutical compositions containing the compounds, and applications of the compounds or compositions in drug preparation. The medicine can be used as kinase inhibitors such as ABL, ABL-T315I, KIT, VEGFR-2 and the like for treating related diseases.

COMPOUNDS USEFUL FOR INHIBITING RAF DIMERS

The disclosure provides compounds of Formula I (Formula I) (c) And the pharmaceutically acceptable salts thereof. The A, B, C, and D rings and the variables, RA, RB, RC, RD, L0, L1, L2

3-ACETYLENYL-PYRAZOLE-PYRIMIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USES THEREOF

The present invention relates to the field of chemical and medicine, more particularly, 3-ethynylpyrazolopyrimidine derivatives and their preparation methods and uses. The invention provides a 3-ethynylpyrazolopyrimidine derivative, and the structure is shown in formula I. The present invention also provides preparation methods and use of 3-ethynylpyrazolopyrimidine derivatives, comprising the compounds and derivatives, and their pharmaceutical compositions for the use of the treatment and prevention of tumors.