100124-30-9

Upstream product

• 1239279-44-7 3-phenyl-2-[(8-bromo-7-hydroxy-5-methoxy-2-methyl-4-oxo-4H-benzopyran-6-ylmethylene)-hydrazono]-thiazolidin-4-one 
• 1239279-42-5 C₁₆H₁₄BrN₃O₅S 
• 1239279-41-4 C₁₅H₁₂BrN₃O₅S 

Downstream Products

• 1239279-40-3 C₁₉H₁₆BrN₃O₃S₂ 
• 1239279-49-2 2-[(8-bromo-7-hydroxy-5-methoxy-2-methyl-4-thioxo-4H-benzopyran-6-ylmethylene)-hydrazono]-3-phenyl-thiazolidin-4-one 
• 1239279-36-7 C₁₉H₁₅BrFN₃O₄S 
• 1239279-35-6 8-bromo-7-hydroxy-5-methoxy-2-methyl-4-oxo-4H-benzopyran-6-carbaldehyde N-phenylthiosemicarbazone 
• 128100-98-1 7-Benzoyl-10-bromo-8-imino-5-methoxy-2-methyl-8H-pyrano[3,2-g]chromen-4-one 
• 135763-11-0 10-Bromo-5-methoxy-2-methyl-8-thioxo-8H-pyrano[3,2-g]chromen-4-one 
• 791-28-6 Triphenylphosphine oxide 
• 135763-10-9 10-Bromo-5-methoxy-8-methyl-pyrano[3,2-g]chromene-2,6-dione 

Relevant academic research and scientific papers

Synthesis and anticonvulsant activity of 4-oxo and 4-thioxo-8- bromobenzopyran derivatives

Several thiosemicarbazones (7 and 8), 1,3-thiazolidin-4-ones (9, 10, 13, 14) and 2-thioxo-1,3-imidazolidin-4-ones (11) have been prepared starting from 8-bromo-7-hydroxy-5-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-carbaldehyde (3) and its 4-thio analogue (4). The anticonvulsant activity of all of the synthesized compounds was evaluated against maximal electrical shock (MES) and subcutaneous pentylenetetrazole (scPTZ) induced seizures. The neurotoxicity was assessed using the rota-rod test. Some of the tested compounds displayed potent anticonvulsant activity in the scPTZ test. ECV Editio Cantor Verlag.