1001336-41-9

Upstream product

• 51175-79-2 methyl α-bromocyclobutanecarboxylate 
• 635-93-8 5-chlorosalicyclaldehyde 

Downstream Products

• 1001336-42-0 E/Z-1-[4-chloro-2-(6-chloro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-phenoxy]-cyclobutanecarboxylic acid methyl ester 

Relevant academic research and scientific papers

3,3'-SPIROINDOLINONE DERIVATIVES AND THEIR USE FOR CANCER

There are provided compounds of the formula (I) or a pharmaceutically acceptable salt or ester thereof wherein X, Y, W, W?,V, V?, V", R1, R2 and R3 are as herein described. The compounds have utility as antiproliferative agents, especially, as anticancer

Spiroindolinone Derivatives

There are provided compounds of the formula and pharmaceutically acceptable salts and esters and enantiomers thereof wherein W, X, X′, Y, V, V′, A, B and R are as described herein. The compounds have utility as antiproliferative agents, especially, as anticancer agents.