1001353-76-9

Basic information

• Product Name: N-(5-tert-butyl-1H-pyrazol-3-yl)-2-chloropyrrolo[1,2-f][1,2,4]triazin-4-amine
• Synonyms: N-(5-tert-butyl-1H-pyrazol-3-yl)-2-chloropyrrolo[1,2-f][1,2,4]triazin-4-amine
• CAS NO: 1001353-76-9
• Molecular Weight: 290.755
• Mol File: 1001353-76-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(5-tert-butyl-1H-pyrazol-3-yl)-2-chloropyrrolo[1,2-f][1,2,4]triazin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-tert-butyl-1H-pyrazol-3-yl)-2-chloropyrrolo[1,2-f][1,2,4]triazin-4-amine(1001353-76-9)
• EPA Substance Registry System: N-(5-tert-butyl-1H-pyrazol-3-yl)-2-chloropyrrolo[1,2-f][1,2,4]triazin-4-amine(1001353-76-9)

Safety Data

• Hazardous Substances Data: 1001353-76-9(Hazardous Substances Data)

Upstream product

• 918538-05-3 2,4-dichloro-pyrrolo[2,1-f][1,2,4]triazine 
• 82560-12-1 3-tert-butyl-1H-pyrazole-5-amine 
• 82560-12-1 5-(tert-butyl)-1H-pyrazol-3-amine 

Relevant articles and documents

PYRROLOTRIAZINE KINASE INHIBITORS

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of such as TrkA, TrkB, TrkC, Jak2, Jak3 and CK2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.