1001353-76-9

Upstream product

• 918538-05-3 2,4-dichloro-pyrrolo[2,1-f][1,2,4]triazine 
• 82560-12-1 5-(tert-butyl)-1H-pyrazol-3-amine 
• 82560-12-1 3-tert-butyl-1H-pyrazole-5-amine 

Relevant academic research and scientific papers

PYRROLOTRIAZINE KINASE INHIBITORS

The invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity thereby making them useful as anticancer agents and for the treatment of Alzheimer's Disease.

PYRROLOTRIAZINE KINASE INHIBITORS

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of such as TrkA, TrkB, TrkC, Jak2, Jak3 and CK2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.