1001353-76-9

Upstream product

• 918538-05-3 2,4-dichloro-pyrrolo[2,1-f][1,2,4]triazine 
• 82560-12-1 5-(tert-butyl)-1H-pyrazol-3-amine 
• 82560-12-1 3-tert-butyl-1H-pyrazole-5-amine 

Relevant academic research and scientific papers

PYRROLOTRIAZINE KINASE INHIBITORS

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of such as TrkA, TrkB, TrkC, Jak2, Jak3 and CK2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.

PYRROLOTRIAZINE KINASE INHIBITORS

The invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity thereby making them useful as anticancer agents and for the treatment of Alzheimer's Disease.