1001395-75-0

Upstream product

• 1117752-16-5 (6S,7S)-(1-methylethyl)-(4,5,6,7-tetrahydro-7-hydroxy-2-oxoimidazo[4,5,1-jk][1]benzazepin-6-yl)carbamic acid phenylmethyl ester 
• 117827-79-9 (6R,7R)-rel-4,5,6,7-tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]imidazo[4,5,1-jk][1]benzazepin-2(1H)-one 

Downstream Products

• 1117752-22-3 (+)-Zilpaterol hydrochloride 

Relevant academic research and scientific papers

Zilpaterol Enantiomer Compositions and Methods of Making and Using Such Compositions

This invention is directed generally to zilpaterol enantiomer compositions and, in particular, to compositions comprising the 6R,7R zilpaterol enantiomer. This invention is also directed to processes for making such compositions; methods for using such compositions to, for example, increase the rate of weight gain, improve feed efficiency, and/or increase carcass leanness in livestock, poultry, and/or fish; and uses of such compositions to make medicaments. This invention is further directed to methods for determining the absolute configurations of zilpaterol enantiomers.

Synthesis and pharmacological characterization of β2- adrenergic agonist enantiomers: Zilpaterol

The β-adrenergic agonist 1 (zilpaterol) is used as production enhancer in cattle. Binding experiments of separated enantiomers on recombinant human β2-adrenergic and μ-opioid receptors and functional studies showed that the (-)-1 enantiomer acc