100144-30-7Relevant academic research and scientific papers
Tandem Pd(II)-catalyzed vinyl ether exchange-claisen rearrangement as a facile approach to γ,δ-unsaturated aldehydes
Wei, Xudong,Lorenz, Jon C.,Kapadia, Suresh,Saha, Anjan,Haddad, Nizar,Busacca, Carl A.,Senanayake, Chris H.
, p. 4250 - 4253 (2007)
(Chemical Equation Presented) A sequential allyl vinyl ether formation-Claisen rearrangement process catalyzed by a palladium(II)- phenanthroline complex is reported. The effects of allylic alcohol structure, type of vinylating agent, and palladium catalysts are discussed. This method provides a convenient approach to γ,δ unsaturated aldehydes under mild conditions that avoid the use of toxic Hg(II) catalysts. The new methodology has been successfully demonstrated on the kilogram scale.
SYNTHESIS OF UNSATURATED BICYCLIC LACTONES AND ACETALS VIA PALLADIUM-PROMOTED CYCLIZATION OF CYCLIC ALLYLIC ALCOHOLS
Larock, Richard C.,Stinn, Dean E.
, p. 2767 - 2770 (2007/10/02)
Unsaturated bicyclic lactones are readily prepared by converting cyclic allylic alcohols to the corresponding α-chloromercurio acetate esters and reacting them with Li2PdCl4.The corresponding acetals can be synthesized directly by reaction of the allylic
